Medical Science Dental Stem Cell : A Review

Dentistry is likely to be revolutionized by biological therapies based on growth and differentiation factors that accelerate and/or induce a natural biological regeneration. Induced pluripotent stem cell-based therapy for treating genetic disorders has become an interesting field of research in recent years. However, there is a paucity of information regarding the applicability of induced pluripotent stem cells in dental research. It has been reported that postnatal stem cells are present in adult tissues such as bone marrow, liver, muscle, dental pulp, and periodontal ligament. Cell-based tissue repair of the tooth and tooth supporting periodontal ligament is a new attractive approach that complements traditional restorative or surgical techniques for replacement of injured or pathologically damaged tissues. Recent attention has been focused on tissue engineering and on the properties of these cells: Adult dental stem cells can differentiate into many dental components, such as dentin, periodontal ligament, cement and dental pulp tissue.